V. Rau, G. A15. 2010, 2012). 2), endothelial cells occasionally contained single, variably sized, eosinophilic or amphophilic smudged intranuclear inclusions (, ). One was a lethal case that occurred in 2002 in an adult wild-born zoo elephant that has not previously been reported on (NAP20), and two came from surviving mildly symptomatic elephants with transient viremia and trunk wash fluid shedding (NAP33 and NAP45). From August 2011 until October 2011, before the change in hierarchy, elephants B, C and D showed elevated levels of EEHV.

If they find worms they should consult a veterinarian. Sources of EEHV genome DNA.The six cases of viremic EEHV in captive-born North American juvenile elephants for which we have carried out detailed DNA sequence analysis here are summarized in Table 1. The 180-kb genome consists of a unique segment bounded by a pair of direct terminal repeats. DNA was extracted from stored frozen necropsy tissue samples after mincing with the use of standard procedures (Latimer et al., 2011). Time period 2 (no animal pregnant) was from March 27, 2012 to May 22, 2012 (two months), and time period 3 (pregnancy 2) was from May 23, 2012 to March 20, 2014 (samples were taken for 11 months during this period). This study reveals an unexpected detrimental role of type I interferons in Sendai virus pathogenesis. The extreme left side of the genome (outside gene E1) contains several segments, including a set of 17-bp tandem repeats as well as a cluster of 8-bp palindromic cyclic AMP (cAMP) response elements (CREs) that have high-level homology to repetitive sequences present within the terminal repeats of the other EEHV genomes.

Following the necropsy, Malee will be cremated. Chai paces on her front legs while bobbing her head. Prog. Several recent reports from longitudinal studies of EEHV shedding in zoo herds (Stanton and others 2010, Hardman and others 2011) have indicated that EEHV-1 shedding detected by trunk washes may be increased during pregnancy; this trunk secretion could present a possible transmission route to juveniles and neonates. I am beyond grateful for this show of support. Because of her veterinary degree, she was eligible to apply for a National Institutes of Health K08 grant, which supports research training for people with clinical degrees. Herpes has been known to kill elephants within 24 hours.

Two recent examples are Alex Rines and Vinnie Christiano. Food was not withheld prior to drug administration, and the elephants had ad libitum access to hay and water. 1998. Separating Asian and African elephants could prevent more deaths, he added. The calf is the result of artificial insemination with sperm from three donors. But any happiness that this family unit would know was short-lived. The Saint Louis Zoo cares about elephants in zoos and in the wild.

Phylogenetic (or family tree) analysis of this data has revealed a great deal of genetic variability amongst and within the many EEHV types that infect Asian and African elephants. Proc American Associaton of Zoo Veterinarians and Assoc of Reptile and Amphibian Veterinarians. Dr. K. Director of Veterinary Care. Dr. Pearson’s interest in elephants was fueled nearly half a century ago when she became involved in elephant conservation through Save the Elephants.

Low levels of multiples types of elephant endotheliotropic herpesvirus (EEHV-6, EEHV-2B, and EEHV-3A) were detected in spleen samples, but not in heart samples. Chris Draper, senior scientific researcher for the Born Free Foundation, said: “The zoo industry is currently engaged in a seemingly desperate search for cases of this virus in wild elephants, but the overwhelming evidence to date is that EEHV is a primarily a killer of captive elephants. “Once again we are mourning,” said zoo spokeswoman Claudia Bienek. The link below, Table 1, shows the normal physiological values for elephants. The Asian elephant has four subspecies: Sri Lankan, Indian, Sumatran and Malaysian. Chronic underspenders can be so terrified about running out of money that they put off health care, ignore needed home repairs or descend into hoarding, says financial planner Rick Kahler of Rapid City, South Dakota. Dr.

For the first edition of our Customer Stories series, we’re heading to Kenya with elephant researcher Virginia R. N2 – A decade ago, Richman et al.1 reported in Science about an unusual acute hemorrhagic disease in Asian elephant calves that was associated with systemic infection by a novel herpesvirus named elephant endotheliotropic herpesvirus (EEHV). On Wednesday, without announcement or ado, the Woodland Park Zoo packed Bamboo and Chai, its two remaining elephants, off to the Oklahoma City Zoo. Bertrand Bouchard, Bounmy Xaymountry, Nikorn Thongtip, Preeda Lertwatcharasarakul, and Worawidh Wajjwalku (2014) FIRST REPORTED CASE OF ELEPHANT ENDOTHELIOTROPIC HERPES VIRUS INFECTION IN LAOS. This complex disease is having a catastrophic effect on the global conservation of the Asian elephant and we want to find a solution to the problem as soon as possible to stop more elephants from dying from this lethal disease.